, , , , , , , Visualization of three pathways for macromolecule transport across cultured endothelium and their modification by flow.” American Journal of Physiology – Heart and Circulatory Physiology doi:10.1152/ajpheart.00218.2017
: 10.1098/rsif.2016.0761, , Ultrasound imaging velocimetry with interleaved images for improved pulsatile arterial flow measurements: a new correction method, experimental and in vivo validation.” Journal of the Royal Society Interface doi
Mohamied Y., Sherwin S.J., Weinberg P.D. (2016) “Understanding the fluid mechanics behind transverse wall shear stress.” Journal of Biomechanics doi: 10.1016/j.jbiomech.2016.11.035.
Chooi K.Y., Comerford A., Sherwin S.J., Weinberg P.D. (2016) “Intimal and medial contributions to the hydraulic resistance of the arterial wall at different pressures: a combined computational and experimental study” Journal of the Royal Society Interface, ISSN: 1742-5689
Chooi K.Y., Comerford A., Cremers S.J., Weinberg P.D. (2016) “Role of endothelial permeability hotspots and endothelial mitosis in determining age-related patterns of macromolecule uptake by the rabbit aortic wall near branch points” Atherosclerosis, Vol: 250, Pages: 77-83
Leow, C.H., Bazigou, E., Eckersley, R.J., Yu, C.H.Y., Weinberg, P.D. and Tang, M-X. (2015) “Flow velocity mapping using high frame-rate plane wave ultrasound and microbubble contrast agents” Ultrasound in Medicine and Biology 41:2913-2925
Rowland, E. M., Mohamied, Y., Chooi, K. Y., Bailey, E. L. and Weinberg, P. D. (2015) “Comparison of statistical methods for assessing spatial correlations between maps of different arterial properties” Journal of Biomechancial Engineering 137. doi: 10.1115/1.4031119
Bailey, E.L., Bazigou, E., Sowinski, P.S.J and Weinberg, P.D. (2015) “Mass Transport Properties of The Rabbit Aortic Wall” PLoS ONE 10:e0120363
Mohamied, Y., Rowland, E.M., Bailey, E.L., Sherwin, S.J., Schwartz, M.A. and Weinberg, P.D. (2015) “Change of direction in the biomechanics of atherosclerosis.” Annals of Biomedical Engineering 43:16-25.
Comerford, A., Chooi, K.Y., Nowak, M., Weinberg, P.D. and Sherwin, S. J. (2015) “A combined numerical and experimental framework for determining permeability properties of the arterial media” Biomechanics and Modeling in Mechanobiology 14:297-313.
Mohri, Z., Rowland, E.M., Clarke, L.A., De Luca, A., Peiffer, V., Krams, R., Sherwin, S.J., and Weinberg, P.D. (2014) “Elevated uptake of plasma macromolecules by regions of arterial wall predisposed to plaque instability in a mouse model.” PLoS ONE 9:e115728
Peiffer, V., Sherwin, S.J. and Weinberg, P.D. (2013) “Computation in the rabbit aorta of a new metric – the transverse wall shear stress – to quantify the multidirectional character of disturbed blood flow.” Journal of Biomechanics 46: 2651–2658.
Alastruey, J., Hunt, A.A.E., and Weinberg, P.D. (2013) “Novel Wave Intensity Analysis of Arterial Pulse Wave Propagation Accounting for Peripheral Reflections.” International Journal For Numerical Methods In Biomedical Engineering Oct 16. doi: 10.1002/cnm.2602.
Vincent, P.E. and Weinberg, P.D. (2013) “Flow Dependent Concentration Polarization and the Endothelial Glycocalyx Layer: Multi-Scale Aspects of Arterial Mass Transport and their Implications for Atherosclerosis” Biomechanics and Modeling in Mechanobiology. Invited Review, DOI 10.1007/s10237-013-0512-1
Zhou, B., Fraser, K.H., Poelma, C., Mari, J-M., Eckersley, R.J., Weinberg, P.D. and Tang, M-X. (2013) “Ultrasound Imaging Velocimetry: effect of beam sweeping on velocity estimation” Ultrasound in Biology and Medicine 39:1672-1681.
Lomax, M.A., Karamanlidis, K., Laws, J., Cremers, S.G., Weinberg, P.D. and Clarke, L. (2013) “Pigs fed saturated fat/cholesterol have a blunted hypothalamic-pituitary-adrenal function, are insulin resistant and have decreased expression of IRS-1, 4 PGC1α and PPARα.” Journal of Nutritional Biochemistry 24: 656-663.
Peiffer, V., Sherwin, S.J. and Weinberg. P.D. (2013) “Does low and oscillatory wall shear stress correlate spatially with early atherosclerosis? A systematic review.”Cardiovascular Research 99: 242-250.
Peiffer, V., Bharath A.A., Sherwin, S.J. and Weinberg P.D. (2013) “A novel method for quantifying spatial correlations between patterns of atherosclerosis and haemodynamic factors.” Journal of Biomechanical Engineering 135: 021023.
Clarke, L.A., Mohri, Z., Weinberg, P.D. (2012) “High-throughput en face mapping of arterial permeability using tile-scanning confocal microscopy.” Atherosclerosis 224; 417-425.
Van Doormaal, M.A., Kazakidi, A., Wylezinska, M., Hunt, A., Tremoleda, J.L., Protti, A., Borhaus, Y., Gsell, W., Weinberg, P.D. and Ethier, CR. (2012) “Hemodynamics in the mouse aortic arch computed from MRI-derived velocities at the aortic root.” Journal of the Royal Society – Interface 9: 2834-2844.
Peiffer, V., Rowland, E.M., Cremer, S.G., Weinberg, P.D. and Sherwin, S.J. (2012) “Effect of aortic taper on patterns of blood flow and wall shear stress in rabbits: association with age” Atherosclerosis 223: 114-121.
Poelma, C., van der Mijle, R., Mari, J-M; Tang, M., Weinberg, P., Westerweel, J. “Ultrasound imaging velocimetry: toward reliable wall shear stress measurements.” European Journal of Mechanics – B Fluids doi 10.1016/j.euromechflu.2012.03.003
Warboys, C.M., Overby, D.R. and Weinberg, P.D. (2012) “Dendritic cells lower the permeability of endothelial monolayers.” Cellular and Molecular Bioengineering 5: 184-193.
Potter, C.M., Schobesberger, S., Lundberg, M., Weinberg, P.D., Mitchell, J.A. and Gorelik, J. (2012) “Shape and compliance of endothelial cells exposed to different shear stress patterns in vitro or selected from different regions of the aorta: assessment by scanning ion conductance microscopy.” PLoS ONE 7:e31228.
Vincent, P.E., Plata, A.M., Hunt, A. A. E., Weinberg, P.D. and Sherwin, S.J. (2011) “Blood Flow in the Rabbit Aortic Arch and Descending Thoracic Aorta” Journal of the Royal Society – Interface 8: 1708-1719. *Featured on front cover of journal.
Iftikhar, S., Bond, A.R., Wagan, A.I., Weinberg, P.D. and Bharath, A.A. (2011) “Segmentation of Endothelial Cell Boundaries of Rabbit Aortic Images using Machine Learning Approach.” International Journal of Biomedical Imaging 2011:270247.
Kazakidi, A., Plata, A.M., Sherwin, S.J. and Weinberg, P.D. (2011) “Effect of reverse flow on the pattern of wall shear stress near arterial branches” Journal of the Royal Society – Interface 8: 1594-1603.
Cremers, S.G., Wolffram, S.J. and Weinberg, P.D. (2011) “Atheroprotective effects of dietary L-arginine increase with age in cholesterol-fed rabbits” British Journal of Nutrition105: 1439–1447.
Bond, A.R., Iftikhar, S., Bharath, A.A. and Weinberg, P.D. (2011) “Morphological evidence for a change in the pattern of aortic wall shear stress with age.” Arteriosclerosis, Thrombosis and Vascular Biology. 31:543-550.
Potter, C.M.F., Lundberg, M.H., Harrington, L.S., Warboys, C.M., Warner, T.D., Berson, R.E., Moshkov, A.V., Gorelik, J., Weinberg, P.D. and Mitchell, J.A. (2011) “Role of shear stress in endothelial cell morphology and expression of cyclooxygenase isoforms.” Arteriosclerosis, Thrombosis and Vascular Biology 31: 384-391.
Poelma, C., Mari, J.M., Foin, N., Tang, M-X., Krams, R., Caro, C.G., Weinberg, P.D. and Westerweel, J. 2011 “3D flow reconstruction using ultrasound PIV” Experiments in Fluids 50: 777–785.
Vincent, P.E., Sherwin, S.J. and Weinberg, P.D. (2010) “The Effect of the Endothelial Glycocalyx Layer on Concentration Polarisation of Low Density Lipoprotein in Arteries”Journal of Theoretical Biology 265:1-17.
Warboys, C.M., Berson, R.E., Mann, G.E., Pearson, J.D. and Weinberg, P.D. (2010) “Acute and chronic exposure to shear stress have opposite effects on endothelial permeability to macromolecules” American Journal of Physiology – Heart and Circulatory Physiology 298: H1850-H1856.
Bond, A.R., Ni, C-W., Jo, H. and Weinberg, P.D. (2010) “Intimal cushions and endothelial nuclear elongation around mouse aortic branches and their spatial correspondence with patterns of lipid deposition” American Journal of Physiology – Heart and Circulatory Physiology 298: H536-H544.
Alastruey, J., Nagel, S.R., Nier, B.A., Hunt, A.A.E., Weinberg, P.D., Peiró, J. (2009) “Modelling pulse wave propagation in the rabbit systemic circulation to assess the effects of altered nitric oxide synthesis” Journal of Biomechanics 42: 2116-2123.
Palombo, F., Weinberg, P.D. and Kazarian, S.G. (2009) “Measurement of drug and macromolecule diffusion across atherosclerotic rabbit aorta ex vivo by Attenuated Total Reflection-Fourier Transform Infrared Imaging” Journal of Biomedical Optics 14: 044008.
Vincent, P.E., Sherwin, S.J. and Weinberg, P.D. (2009) “The Effect of a Spatially Heterogeneous Transmural Water Flux on Concentration Polarisation of Low Density Lipoprotein in Arteries” Biophysical Journal 96: 3102-3115.
Palombo, F., Cremers, S.G., Weinberg, P.D. and Kazarian, S.G. (2009) “Application of FTIR spectroscopic imaging to study effects of age and dietary L-arginine on aortic lesion composition in cholesterol-fed rabbits” Journal of the Royal Society Interface, 6: 669-680.
Kazakidi, A., Sherwin, S.J., and Weinberg, P.D. (2009) “Effect of Reynolds number and flow division on patterns of haemodynamic wall shear stress near branch points in the descending thoracic aorta” Journal of the Royal Society Interface, 6: 539-548.
Segers, D., Weinberg, P. and Krams R. (2008) “Atherosclerosis: cell biology and lipoproteins – shear stress and inflammation in plaque formation: new evidence.” Current Opinion in Lipidology 19: 627-628.
Vincent, P.E., Sherwin, S.J. and Weinberg, P.D. (2008) “Viscous Flow Over Outflow Slits Covered by an Anisotropic Brinkman Medium: A Model of Flow Above Inter-Endothelial Cell Clefts.” Physics of Fluids Volume: 20 Issue: 6 Article Number: 063106.
Nier, B.A., Carrier, M.J., Harrington, L.S., Weinberg, P.D. (2008) “Evidence for a specific influence of the nitrergic pathway on the peripheral pulse waveform in rabbits”Experimental Physiology 93: 503–512.
Rimbach, G., Boesch-Saadatmandi, C., Frank, J., Fuchs, D., Wenzel, U., Daniel, H., Hall, W.L. and Weinberg, P.D. (2008) “Dietary isoflavones in the prevention of cardiovascular disease – A molecular perspective” Food and Chemical Toxicology 46; 1308-1319.
Staughton, T.J., del Rio, J.D. and Weinberg, P.D. (2007) “Patterns of arterial wall permeability at the left coronary bifurcation in rabbits” Atherosclerosis 196; 207-209.
Weinberg, P.D. and Ethier, C.R. (2007) “Twenty-fold difference in wall shear stress between murine and human aortas” Journal of Biomechanics 40; 1594-1598.
Nier, B.A., Weinberg, P.D., Rimbach, G., Stocklin, E. and Barella, L. (2006) “Differential Gene Expression in Skeletal Muscle of Rats with Vitamin E deficiency” IUBMB Life 58: 540-548.
Ewins, B.A., Vassiliadou, M., Minihane, A.M., Rimbach, G.H. and Weinberg, P.D. (2006) “Techniques for quantifying effects of antioxidants on nitric oxide production and transcription factor nuclear translocation in cultured cells.” Genes and Nutrition 1: 125-132.
Hernandez-Montes, E., Pollard, S.E., Vauzour, D., Jofre-Montseny, L., Rota, C., Rimbach, G., Weinberg, P.D. and Spencer J.P.E. (2006) “Activation of glutathione peroxidase via Nrf1 mediates genistein’s protection against oxidative endothelial cell injury.” Biochemical and Biophysical Research Communications 346: 851-859.
Totta, P., Acconcia, F., Virgili, F., Cassidy, A., Weinberg, P.D., Rimbach, G. and Marino, M. (2005) “Daidzein-sulphate metabolites affect transcriptional and anti-proliferative activities of estrogen receptor-beta in cultured human cancer cells” Journal of Nutrition 135: 2687-2693.
Weinberg, P.D. (2005) “Analysis of the variable effect of dietary vitamin E supplements on experimental atherosclerosis.” Journal of Plant Physiology 162; 823-833.
Cremers, S.G. and Weinberg, P.D. (2005) “Use of a desktop scanner and spreadsheet software for mapping arterial lipid deposition.” Scanning 27; 126-131.
Turner, R., Etienne, N., Garcia Alonso, M., Minihane A.M., Weinberg, P.D. and Rimbach, G.H. (2005) “Antioxidant and cellular activities of olive oil phenolics.” International Journal of Vitamin and Nutrition Research 75(1): 61-70.
Colley, C.S., Kazarian, S.G., Weinberg, P.D. and Lever, M.J. (2004) “Spectroscopic imaging of arteries and atherosclerotic plaques.” Biopolymers 74; 328-335.
Weinberg, P.D. (2004) “Rate-limiting steps in the development of atherosclerosis: the response to influx theory.” Journal of Vascular Research 41; 1-17. Review
Rimbach, G., Weinberg, P.D., de Pascual Teresa, S., Garcia, M., Ewins, B.A., Turner, R., Minihane, A.M., Botting, N., Fairley, B., Matsugo, S., Uchida, Y., Cassidy, A. (2004) “Sulfation of genistein alters its antioxidant properties and its effect on platelet aggregation and monocyte and endothelial function.” Biochimica et Biophysica Acta (General Subjects) 1670; 229-237.
Al-Musawi, S., Bishton, J., Dean, J., Williams, S., Cremers, S.G and Weinberg, P.D. (2004) “Evidence for a reversal with age in the pattern of near-wall blood flow around aortic branches.” Atherosclerosis 172; 79-84.
Staughton, T.J. and Weinberg, P.D. (2004) “Effect of time of day and rabbit strain on patterns of aortic wall permeability.” Experimental Physiology 89; 109-118.
Turner, R., Baron, T., Wolffram, S., Minihane, A.M., Cassidy, A., Rimbach, G., and Weinberg, P.D. (2004) “Effect of circulating forms of soy isoflavones on lipoprotein oxidation.”Free Radical Research 38; 209-216.
Talbot, R. M., del Rio, J.D., Leak D.S. and Weinberg, P.D. (2003) “Oxidation affects the self-aggregation of low density lipoprotein and its inhibition by albumin” Biochimica et Biophysica Acta (Molecular and Cell Biology of Lipids) 1634; 24-29.
Gottstein, N., Ewins, B.A., Ecclestone, C., Hubbard, G.P., Kavanagh, I.C., Minihane, A-M., Weinberg, P.D. and Rimbach, G. (2003) “Effect of genistein and daidzein on platelet aggregation and monocyte and endothelial function.” British Journal of Nutrition 89; 607-616.
Talbot, R.M., del Rio J.D. and Weinberg, P.D. (2003) “Effect of fluid mechanical stresses and plasma constituents on aggregation of low density lipoprotein.” Journal of Lipid Research 44; 837-845.
Rimbach, G.H., Matsugo, S., Ewins, B.E., Vafeidou, K., Turner, S., de Pascual Teresa, S., Minihane, A.M. and Weinberg, P.D. (2003) “Antioxidant and free radical scavenging activity of isoflavone metabolites.” Xenobiotica 33; 913-925.
Ewins, B.A., Majewicz, J., Staughton, T.J. and Weinberg, P.D. (2002) “2-D maps of short-term albumin uptake by the immature and mature rabbit aortic wall around branch points.” Journal of Biomechanical Engineering 124; 684-690.
Weinberg, P. D. (2002) “Disease patterns at arterial branches and their relation to flow.” Biorheology 39; 533-537. Invited paper
Rimbach, G.H., Minihane, A.M., Majewicz, J., Fischer, A., Pallauf, J., Virgili, F. and Weinberg, P.D. (2002) “Regulation of cell signalling by vitamin E” Proceedings of the Nutrition Society 61; 415-425. Invited Review
Staughton, T.J., McGillicuddy, C.J. and Weinberg, P.D. (2001) “Techniques for reducing the interfering effects of autofluorescence in fluorescence microscopy: improved detection of sulphorhodamine B-labelled albumin in arterial tissue” Journal of Microscopy 201: 70-76.
Barnes, S.E. and Weinberg, P.D. (2001) “Strain-dependent differences in the pattern of aortic lipid deposition in cholesterol-fed rabbits” Experimental and Molecular Pathology71; 161-170.
Staughton, T.J., Lever, M.J. and Weinberg, P.D. (2001) “Effect of altered flow on the pattern of permeability around rabbit aortic branches” American Journal of Physiology 281; H53-H59.
Weinberg, P.D., Kengatharan, M., Habens, F., Barnes, S.E., Anggard, E.E. and Carrier, M.J. (2001) “Characteristics of the pulse waveform during altered nitric oxide synthesis in the rabbit” British Journal of Pharmacology 133: 361-370.
McGillicuddy, C.J., Carrier, M.J. and Weinberg, P.D. (2001) “Distribution of lipid deposits around aortic branches of mice lacking low density lipoprotein receptors and apolipoprotein E” Arteriosclerosis, Thrombosis and Vascular Biology 21; 1220-1225.
Richards, J.P. and Weinberg, P.D. (2000) “Distribution of disease around the aorto-coeliac branch of White Carneau pigeons at different ages” Experimental and Molecular Pathology, 66: 95-103.
Javed, Q., Leake, D.S., and Weinberg, P.D. (1999) “Quantitative immunohistochemical detection of oxidised low density lipoprotein in the rabbit arterial wall” Experimental and Molecular Pathology 65: 121-140.
Barnes, S.E. and Weinberg, P.D. (1999) “Two patterns of lipid deposition in the cholesterol-fed rabbit” Arteriosclerosis, Thrombosis and Vascular Biology 19: 2376-2386.
Barnes, S.E. and Weinberg, P.D. (1998) “Contrasting patterns of spontaneous aortic disease in young and old rabbits” Arteriosclerosis, Thrombosis and Vascular Biology 18: 300-308.
Weinberg, P.D., Carney, S.L., Winlove, C.P. and Parker, K.H. (1997) “The contributions of glycosaminoglycans, collagen and other interstitial components to the hydraulic resistivity of porcine aortic wall” Connective Tissue Research 36: 297-308.
Forster, B.A. and Weinberg, P.D. (1997) “Changes with age in the influence of endogenous nitric oxide on transport properties of the rabbit aortic wall near branches” Arteriosclerosis, Thrombosis and Vascular Biology 17: 1361-1368.
Forster, B.A. and Weinberg, P.D. (1997) “Evans’ blue dye abolishes endothelium-dependent relaxation of rabbit aortic rings” Atherosclerosis 129: 129-131.
Forster, B.A., Javed, Q., Leake, D.S., and Weinberg, P.D. (1996) “High-resolution mapping of the frequency of lipid deposits in thoracic aortae from cholesterol-fed and heritable hyperlipidaemic rabbits” Atherosclerosis 120: 249-253.
Sebkhi, A. and Weinberg, P.D. (1996) “Effect of age on the pattern of short-term albumin uptake by the rabbit aortic wall near intercostal branch ostia” Arteriosclerosis, Thrombosis and Vascular Biology 16: 317-327.
Weinberg, P.D., Winlove, C.P. and Parker, K.H. (1995) “The distribution of water in arterial elastin: effects of mechanical stress, osmotic pressure and temperature” Biopolymers35: 161-169.
Sebkhi, A. and Weinberg, P.D. (1994) “Age-related variations in transport properties of the rabbit arterial wall near branches” Atherosclerosis 106: 1-8.
Weinberg, P.D., Winlove, C.P. and Parker, K.H. (1994) “Measurement of absolute tracer concentrations in tissue sections by using digital imaging fluorescence microscopy: application to the study of plasma protein uptake by the arterial wall” Journal of Microscopy 173: 127-141.
Maroudas, A., Wachtel, E., Grushko, G., Katz, E., Weinberg, P. (1991) “Osmotic and mechanical pressure alter the packing of collagen molecules in articular cartilage” Biochimica Biophysica Acta 1073: 285-294.
Weinberg, P.D. (1989) “Effect of tissue processing techniques on the sensitivity of microfluorimetric determinations of tracers in tissue sections” Analytica Chimica Acta 227: 243-249.
Weinberg, P.D. (1989) “Densitometry of photomicrographic negatives for the determination of fluorophores in sections of tissue” Analytica Chimica Acta 227: 235-241.
Maroudas, A., Weinberg, P.D., Winlove, C.P. and Parker, K.H. (1988) “The distributions and diffusivities of small ions in chondroitin sulphate, hyaluronate and some proteoglycan preparations” Biophysical Chemistry 32: 257-270.
Weinberg, P.D. (1988) “Application of fluorescence densitometry to the study of albumin uptake by the rabbit aortic wall up- and downstream of branches” Atherosclerosis 74: 139-148.